Week 7 of the NFL season brings another wave of key injuries with major fantasy football implications. As fantasy managers push toward playoff positioning, understanding how these injuries impact player availability and production is crucial. From Brock Purdy’s lingering toe issue to Kyler Murray’s foot injury, and the return outlooks for stars like CeeDee Lamb, we break down every major injury that could affect your fantasy lineup. Below is your complete NFL Week 7 Injury Recap and Fantasy Impact report, helping you make informed start/sit and roster decisions heading into the weekend.

Quarterbacks

Brock Purdy

Injury: Toe injury

Analysis: Purdy will miss another game as he continues to rehab his toe injury. San Fran is being very careful, as they should, having seen their starting quarterback already re-injure his toe. The big toe is the last point of contact with the ground, meaning it takes on massive forces when throwing or running. Because of its mechanical role in throwing and running, playing through injury can impact a quarterback's throwing power, ability to navigate the pocket, and ability to scramble. Purdy should be able to return soon, but for now, Mac Jones has been playing well enough to carry the Niners.

Kyler Murray

Injury: Foot injury

Analysis: Murray is pushing to return in week 7, but will be a game-time decision after missing week 6 with a foot injury. Video review suggests this is his right foot, which not only would impact his rushing upside but can also impact his ability to push off for throwing power and to step up in the pocket. With so much of Murray's fantasy upside coming from his legs, even if Murray can go this week, expect a considerable dip in fantasy production.

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JJ McCarthy

Injury: High ankle sprain

Analysis: McCarthy is not likely to make his return from a right high ankle sprain this week. A high ankle sprain, keeping a player out for 5 weeks, is almost certainly a grade II injury where true ankle instability is present. If he plays next week, 6 weeks is usually enough to regain enough stability for him to push off his right foot for throwing power, push to step up in the pocket, and scramble when needed. For other positions, re-injury would be a significant risk, but for a primarily pocket passer, re-injury is less of a concern. Quarterbacks historically average no drop-off in fantasy points after a high ankle sprain.

Running Backs

Bucky Irving

Injury: Foot / Shoulder Subluxation

Analysis: Bucky is expected to miss again with both a left foot sprain and a shoulder subluxation. The foot sprain is not to the degree where it needs surgery, but it is continuing to keep him out. The foot is an adaptive structure that quite literally changes its shape while running, and when injury is present, its ability to change shape to adapt to terrain and demands is challenged, making runners slower and less able to change direction. The good news is that whenever Bucky does return, running backs average just a 6% drop in fantasy points.

The shoulder subluxation is another story. A subluxation is a mild version of a dislocation; the head of the humerus does not fully disconnect from the shoulder socket, and less labrum damage occurs, but instability now exists, and re-injury risk will be elevated when he returns.

Josh Jacobs

Injury: Calf Injury / Illness

Analysis: Jacobs has been battling an illness all week, but he also had a "calf injury" added to his list late this week. Jacobs was able to log a full practice on Friday, which is encouraging and suggests his calf injury is incredibly mild. Let's remember that a grade I muscle injury is characterized by little to no muscle damage or strength loss, so as long as Jacobs can play Sunday, he should play well. Running backs average just a 7% dip in fantasy points after a calf injury. For a workhorse like Jacobs, this is not enough to even consider benching. Re-injury is the concern, with a 15-20% chance of worsening his calf injury if he plays, but still, you have to start him if he suits up.

Chuba Hubbard

Injury: Calf injury

Analysis: Hubbard is expected to return after missing two games with a calf injury (re-injury). The calf muscle is critical for acceleration and burst, skills needed for a running back. Still, running backs average just a 7% dip in fantasy points in the first game after a calf injury, which normally would make Hubbard a solid play coming off injury. However, we've all seen his teammate Rico Dowdle go off in Hubbard's absence. Carolina will not tell us what the backfield split will be. Still, with Hubbard already suffering one setback to his calf injury, I would expect they gradually re-integrate him into their offense and let Dowdle be the lead back again this week.

Blake Corum

Injury: Ankle injury

Analysis: Corum has logged a few limited practices and will play in week 7. Ankle injuries impact a runner's ability to change directions quickly and have a high recurrence rate (29%). Running backs average a 7% dip in fantasy points after an ankle injury. Corum is not yet ready to be started in fantasy.

Bam Knight

Injury: Knee injury

Analysis: Knight had a mild knee injury but is cleared from the injury report and ready to play. Mild knee injuries usually lead to soreness and stiffness that respond easily to treatment during the week, and when the athlete is warmed up, it is not a problem at all. Don't expect this to limit Knight this week.

Emari Demercado

Injury: Ankle injury

Analysis: Demercado has been ruled out for week 7 with an ankle injury. Bam Knight and Michael Carter will carry the load for Arizona.

Wide Receivers

Puka Nacua

Injury: Ankle injury

Analysis: Nacua landed awkwardly on his foot and ankle, ultimately being diagnosed with an ankle injury. Long term, this should not be a big problem, and Nacua will become dominant again well before the season ends. In the interim, however, Nacua will miss week 7. The challenge with ankle injuries for a receiver is the loss of stability to quickly change directions while getting in and out of their routes. This is displayed in the data, as receivers average a 10% decline in their fantasy production in the first game after injury. 10% is nothing for Nacua, and fantasy managers can be confident that Nacua will be dominant again, but for less dominant players 10% can be significant.

Re-injury risk is nothing to sneeze at, as ankle injuries have nearly 30% recurrence rates. Nacua has experienced his share of injuries early in his career, but remains an elite player when he returns.

CeeDee Lamb

Injury: High ankle sprain

Analysis: Lamb will make his return this week, three weeks after suffering a left high ankle sprain. High ankle sprains are more significant than lateral (low) ankle sprains and lead to more notable ankle instability. The loss of stability makes it difficult to quickly plant and cut to change direction. The difference in function of a high and low ankle sprain is seen in average time missed, with receivers averaging missing nearly 3 games with a high ankle, and less than one game with a low ankle sprain.

The good news for fantasy owners is that the lengthy time missed from a high ankle sprain generally allows athletes to return at nearly 100%, with receivers averaging no drop-off in fantasy points when they return. Lamb will again be dominant, but re-injury risk is high.

Garrett Wilson

Injury: Knee injury

Analysis: Wilson is out for week 7 with a knee injury reported as a "knee hyperextension". Let's make one thing clear: "knee hyperextension" is NOT a clinical diagnosis; it describes a motion at the joint. Hyperextensions at the knee can put stress on a number of tissues, and his actual injury has not been disclosed. Some of the most common tissues that are stressed with knee hyperextension moments are the ACL (not Wilson's case), PCL (possibly a grade I injury), the meniscus (possible, but clearly not to the degree where he needs surgery), and a bone bruise (possible).

As of the most current reporting, it is likely Wilson will miss a game or two, but this is not a long-term injury. Let's hope more information comes out so we can best assess how this injury will impact Wilson going forward. If this is a grade I PCL injury, expect performance decline for 4-6 weeks. If this is a bone bruise, expect him to play pretty well when he returns.

Mike Evans

Injury: Hamstring Strain

Analysis: Evans will be a game-time decision to play Monday night, attempting to return from a grade II hamstring injury. Evans is 32 years old, and this is his EIGHTH recorded hamstring injury. Age and prior injury are the two biggest risk factors for injury, and neither is working for Evans, who will remain high risk for injury the rest of the season whenever he does return.

On the bright side, he is still really good at football, and the Buccaneers' receiving corps is decimated. Receivers average a 15% decline in fantasy production after a hamstring injury, but Evans still may be worth the start whenever he does return.

Emeka Egbuka

Injury: Hamstring Strain

Analysis: The 23-year-old rookie will be a game-time decision Monday night as he rehabs from his first-ever recorded hamstring injury. Egbuka's rest of season outlook is vastly different than his teammate above, Mike Evans. Hamstring injuries have extremely high recurrence rates (20-30%), and if Egbuka plays Monday night, this risk will apply. But with this being Egbuka's first ever and being just 23 years old, if Tampa holds him out this week (and possibly next), his re-injury rate will be far lower than the 32-year-old Evans.

The expected performance dip of 15% will apply whenever Egbuka returns, especially if it is this week; however, if Tampa holds him out of weeks 7 and 8, he may be able to ride the week 9 bye into a productive week 10.

Ricky Pearsall

Injury: PCL sprain

Analysis: Pearsall will miss another game with a PCL sprain. The PCL's role in stability and proprioceptive feedback is critical for an athlete's ability to quickly and confidently plant and change directions. Pearsall will need to continue to rehab hard to regain the lost stability before he can safely return to the field. Players usually look slow in the first few games after a PCL injury, but fantasy managers can expect Pearsall to look good again come November.

Marvin Harrison Jr.

Injury: Concussion

Analysis: Harrison has quickly cleared the NFL's concussion protocol and will play. We do not typically see a drop in fantasy production after a concussion.

Chris Godwin

Injury: Fibula

Analysis: Godwin will miss another game with a fibula injury. This is reportedly in a different location than his fracture site, but it is still likely a compensatory injury secondary to the surgery. It's nearly impossible to regain normal ankle mechanics after such a significant injury and surgery, and thus, Godwin will remain high risk for injury going forward.

DJ Moore

Injury: Hip / Groin

Analysis: Just a few days after being hospitalized, Moore has cleared the injury tag and will play through a hip/groin injury. Video review shows Moore slamming into the ground, landing on his hip, likely leading to some bruising (hip pointer). With a hip pointer, as soon as the bruising subsides, function is fully restored, and I would not expect the hip to limit Moore this week.

Groin injuries can impact change of direction and route running, but practicing in full just five days after injury shows us this is no worse than a grade I injury with no true muscle damage or loss of strength. Receivers average no drop off in fantasy points after a groin injury, and Moore should not be affected by either injury this week.

Stefon Diggs

Injury: Chest Injury

Analysis: Diggs was limited early week with a chest injury, but did log a full practice on Friday. Chest injuries are usually injuries to the anterior ribs or the costal cartilage (rib cartilage) and can be thought of similarly to rib injuries. Several major muscles attach to the ribs, with it being described as a chest injury, we are looking at the pectoralis muscles, obliques, and intercostals primarily. The pecs are critical for moving the arm to catch, block, and hold the football, the obliques twist the torso to make a catch and brace for impact, and the intercostals are big breathing muscles.

For the most part, players can play through injury, but this comes with a cost to their fantasy output. Receivers average a 16% dip in fantasy points in the first game after a chest injury. Diggs has been solid but inconsistent in year one post-ACL surgery, but this may be a week to think twice about starting him.

Jakobi Meyers

Injury: Toe and Ankle injury

Analysis: Meyers is dealing with both toe and ankle injuries ahead of week 7 and only logged one limited practice. Toe injuries impact explosiveness in the straight line, and ankle injuries impact lateral agility. Both injuries lead to performance declines for receivers, averaging a 10% decline in fantasy points in game one after an ankle sprain, and 10% decline after a toe injury as well. Both have high rates of re-injury, another factor fantasy managers need to consider. All together, Meyers is a flex at best this week if he can play.

Calvin Ridley

Injury: Hamstring injury

Analysis: Ridley is unlikely to play through a right hamstring injury suffered in week 6. Ridley is 30 years old, and healing is not as efficient as it once was. The hamstring is most stressed with top speed sprinting, which a receiver like Ridley is routinely doing. This is why hamstring injuries impact receivers more than any other position, and one reason that recurrence rates are so high. Receivers average missing just under two games with a hamstring injury; it is likely Ridley meets and possibly exceeds this average. Whenever he returns, receivers average a 15% decline in fantasy points.

Quentin Johnston

Injury: Hamstring injury

Analysis: Johnston is set to return after missing one game with a hamstring injury. While his injury is likely not 100%, his full participation in practice is encouraging. Still, there is reason for concern. Johnston makes his living downfield, and receivers are the position most impacted by hamstring injuries. When a hamstring injury is present, it is difficult to reach top speeds, and the player runs a high risk of re-injury (20-30%). Receivers average a 15% dip in fantasy points in the first game coming off a hamstring injury, but with Johnston's playing style, this number may be higher, and fantasy managers need to think twice about playing him this week.

Darnell Mooney

Injury: Hamstring injury

Analysis: Mooney, who is now two weeks removed from the onset of his hamstring injury, is trending towards being a game-time decision. A hamstring injury is going to affect Mooney's playing style more than most athletes. As mentioned with Johnston above, the hamstring is a critical sprinting muscle, especially at top speeds. Mooney is a deep threat, and as such, if he can play, he would likely see a performance dip in this first game back from injury. Re-injury rate of 20-30% is also a concern enough to let Mooney sit this week.

Christian Watson

Injury: ACL tear

Analysis: Watson is making great strides, but is not yet ready to play in week 7 as he continues to rehab his ACL tear. Whenever Watson does return, be mindful that receivers average a 28% dip in fantasy points per game in the first year after an ACL tear.

KaVontae Turpin

Injury: Foot injury

Analysis: Turpin will return this week after missing two games with a foot injury. Turpin's playing style makes this a tricky injury to play well through. Foot injuries make it difficult to quickly change direction, which will impact his ability to get open and run after the catch. Receivers average a whopping 50% dip in fantasy points in game one after a foot sprain.

Jalen Coker

Injury: Quad injury

Analysis: Coker is expected to make his debut after missing significant time with a quad injury. In the NFL, receivers average missing just over one game with a quad injury. Coker's injury was severe enough to keep him out for the first six weeks of the season. The quad is a critical speed and power muscle, and when a significant injury is present, sprinting, cutting, and jumping are extremely difficult. The good news for Coker is that having two months to rehab should have him at 100% which will reduce re-injury risk and allow him to play well from the start. Receivers average no drop-off in fantasy points after a quad injury.

Josh Downs

Injury: Concussion

Analysis: Downs will not clear the concussion protocol ahead of week 7. We will check back in on his status next week.

Tight Ends

George Kittle

Injury: Hamstring injury

Analysis: Kittle is trending toward making his return in week 7. With a month and a half to rehab, Kittle should be close to 100% functionally. The challenge for Kittle won't be fantasy production; tight ends average just a 7% dip in fantasy points in game one after a hamstring. The challenge is the re-injury risk. At baseline, hamstrings have a 20-30% recurrence rate, but Kittle is 32, and this is his 5th career hamstring injury. Not a good combination from an injury risk factor perspective. Still a great start though!

Brock Bowers

Injury: PCL sprain

Analysis: Bowers is unlikely to play again in week 7 as he continues to rehab his left PCL injury from week one. PCL injuries are challenging to play through due to the significant passive stability and proprioceptive role the PCL plays in the knee. In order to return and play well, the neuromuscular control needs to make up for this lost stability. Bowers can return and play well, but it often takes 4-6 weeks. It's possible Bowers made things worse by attempting to play in weeks 2-4. Expect him to look better after their week 8 bye.

David Njoku

Injury: Knee injury

Analysis: Like Garrett Wilson, Njoku's left knee was forced into hyperextension. We had a clear video shot of Njoku's injury, which shows his hip was slightly laterally rotated while his knee was forced into hyperextension, putting stress on the LCL, posterolateral corner, as well as potentially leading to a bone bruise. The good news is the total amount of hyperextension was not significant, so very unlikely that any full-blown tears occurred, but it is likely dealing with a bone bruise and possibly a grade I sprain of the LCL or PCL.

Njoku will likely be limited when he returns, and this could lead to a temporary dip in fantasy production. Rookie Harold Fannin Jr. has a great opportunity to continue his excellent first season.

Zach Ertz

Injury: Shoulder / Calf

Analysis: Ertz is questionable with both shoulder and calf injuries. Both injuries present functional challenges for a tight end. The shoulder injury makes it difficult to block, which leads to an 11% dip in snap rate after a shoulder injury. The calf injury makes it difficult to get down the field, but these days, Ertz isn't running many routes downfield, and the calf should be less of a concern. These injuries will combine to make it difficult for Ertz to have a big game this week, but he could still be bailed out by a touchdown if he can play.